Akademische Laufbahn
- 1990 – 1997 Studium der Humanmedizin, Universität zu Lübeck
- 2000 Dissertation: Interaktionen von Agmatin mit dem kardiovaskulären System und dem sympathischen Nervensystem (summa cum laude)
- 1997 – 1998 Wiss. Assistent, Institut für experimentelle und klinische Pharmakologie und Toxikologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck
- 1998 – 2002 Wiss. Assistent, Med. Klinik II, Universität zu Lübeck
- 2002-2005 Forschungsaufenthalt an der Cornell University, Weill Medical College New York, USA
- 2005-2007 Wissenschaftlicher Assistent, Med. Klinik II, Universität zu Lübeck
- 2007 – 2008 Funktionsoberarzt der Med. Klinik II, Universität zu Lübeck
- 05/2007 Facharzt für Innere Medizin
- 06/2007 Zusatzbezeichnung Notfallmedizin, inkl. „Rettung See“
- 07/2007 Fachgebietsbezeichnung für Kardiologie
- 09/2008 - 01/2014 Oberarzt und Leiter des Katheter-interventionellen Programms von strukturellen Herzerkrankungen am Asklepios-Klinikum St. Georg, Hamburg
- 05/2010 Habilitation: Neu identifizierte präsynaptische Regulations-Mechanismen des peripheren sympathischen Nervensystems, Universität zu Lübeck
- 02/2014 - 10/2018 Geschäftsführender Oberarzt und Leiter des katheter-interventionellen Programms von strukturellen Herzerkrankungen der Klinik für Allgemeine und Interventionelle Kardiologie des Universitären Herz- und Gefäßzentrums, Hamburg
- 02/2014 Umhabilitation: Hämodynamische Veränderungen nach Volumenreduktion durch das Parachute-Verfahren, Universität Hamburg
- 03/2018 Außerplanmäßige Professur (APL) an der Universität Hamburg
- 10/2018 - 09/2021 Chefarzt der Kliniken für Kardiologie, Angiologie und Internistische Intensivmedizin am katholischen Marienkrankenhaus, Hamburg
- 09/2021 - 05/2022 Direktor der Klinik für Innere Medizin und Leiter der Abteilungen für Kardiologie, Angiologie, Internistische Intensivmedizin, Pneumologie, Nephrologie, Diabetologie und Geriatrie im Bundeswehrzentralkrankenhaus Koblenz
- seit 05/2022 Sektionsleitung für Innovative interventionelle Herzmedizin der Klinik für Kardiologie, Herz- und Gefäßzentrum Bad Bevensen
Wissenschaftliche Schwerpunkte
- Interventionelle Therapie von strukturellen Herzerkrankungen
- Translationale Device-Studien (first-in-man, CE-Zulassung) zur Behandlung der Aortenstenose, Mitralinsuffizienz, Trikuspidalinsuffizienz, Herzinsuffizienz etc.
- Biomarkerkinetiken beim perkutanen Klappenersatz
- Hämodynamik und Druckvolumen-Verhältnisse im Rahmen interventioneller Eingriffe bei strukturellen Herzerkrankungen (Parachute, MitraClip, TAVI)
- Integrative invasive und nichtinvasive Bildgebungskonzepte bei strukturellen Herzerkrankungen
- Durchführung und Planung nationaler Multicenter-Studien
- Neurohumorale Regulationsmechanismen während Ischämie und Reperfusion
- Modulationsmechanismen der sympathischen Nervenaktivität
- endotheliale Dysfunktion, Inflammation, Sepsis, Hämostasiologie
Sonstige Aktivitäten
- Mitglied der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislauferkrankungen; Arbeitsgruppen-Mitglied der AG 25 Pulmonale Hypertonie, AG 26 Aortenerkrankungen und der AG 6 Interventionelle Kardiologie
- Mitglied der Deutschen Gesellschaft für Innere Medizin mit regelmäßiger aktiver Beteiligung an deren Kongressen
- Mitglied der European Society of Cardiology (ESC)
- Mitglied der „Heart Failure Association“ der ESC
- Mitglied der „International Society for Minimally Invasive Cardiac Surgery“ (ISMICS)
- Guest Faculty Mitglied: EuroPCR (seit 2010), PCR London Valves (seit 2011), Catheter Interventions in Congenital, Structural and Valvular Heart Disease, CSI (seit 2011), Transcatheter Valve Therapies, TVT (seit 2012), Transcatheter Cardiovascular Therapeutics, TCT (seit 2012) und International Conference for Innovations in Cardiovascular Systems, ICI (seit 2014)
- Mitglied beim Institut für Qualitätssicherung und Transparenz im Gesundheitswesen (IQTIG) im Rahmen der Qualitätssicherung mit aktiver Beteiligung an der Durchführung des strukturierten Dialogs
Ausgewählte Publikationen
- Thirty-day outcomes of the Cardioband tricuspid system for patients with symptomatic functional tricuspid regurgitation: The TriBAND study.
Nickenig G, Friedrichs KP, Baldus S, Arnold M, Seidler T, Hakmi S, Linke A, Schäfer U, Dreger H, Reinthaler M, von Bardeleben RS, Möllmann H, Weber M, Roder F, Körber MI, Landendinger M, Wolf F, Alessandrini H, Sveric K, Schewel D, Romero-Dorta E, Kasner M, Dahou A, Hahn RT, Windecker S.
EuroIntervention. 2021 May 18:EIJ-D-21-00300. doi: 10.4244/EIJ-D-21-00300. Epub ahead of print. - Transcatheter Tricuspid Valve Intervention in Patients With Right Ventricular Dysfunction or Pulmonary Hypertension: Insights From the TriValve Registry.
Muntané-Carol G, Taramasso M, Miura M, Gavazzoni M, Pozzoli A, Alessandrini H, Latib A, Attinger-Toller A, Biasco L, Braun D, Brochet E, Connelly KA, de Bruijn S, Denti P, Deuschl F, Lubos E, Ludwig S, Kalbacher D, Estevez-Loureiro R, Fam N, Frerker C, Ho E, Juliard JM, Kaple R, Kodali S, Kreidel F, Harr C, Lauten A, Lurz J, Monivas V, Mehr M, Nazif T, Nickening G, Pedrazzini G, Philippon F, Praz F, Puri R, Schäfer U, Schofer J, Sievert H, Tang GHL, Khattab AA, Andreas M, Russo M, Thiele H, Unterhuber M, Himbert D, Urena M, von Bardeleben RS, Webb JG, Weber M, Windecker S, Winkel M, Zuber M, Hausleiter J, Lurz P, Maisano F, Leon MB, Hahn RT, Rodés-Cabau J.
Circ Cardiovasc Interv. 2021 Feb; 14(2):e009685. doi: 10.1161/ CIRC INTERVENTIONS. 120.009685. Epub 2021 Feb 5. - One-year clinical outcomes of a novel transcatheter heart valve to treat degenerated surgical valves - The "VIVALL" study.
Schäfer U, Butter C, Landt M, Frerker C, Treede H, Schirmer J, Koban C, Allali A, Schmidt T, Charitos E, Nikolayevska O, Conradi L.
EuroIntervention. 2021 Mar 30:EIJ-D-20-01241. doi: 10.4244/EIJ-D-20-01241. Epub ahead of print. - The ACURATE neo2 valve system for transcatheter aortic valve implantation: 30-day and 1-year outcomes.
Möllmann H, Holzhey DM, Hilker M, Toggweiler S, Schäfer U, Treede H, Joner M, Søndergaard L, Christen T, Allocco DJ, Kim WK.
Clin Res Cardiol. 2021 Jun 20. doi: 10.1007/s00392-021-01882-3. Epub ahead of print. - Outcomes of transcatheter tricuspid valve intervention by right ventricular function: a multicentre propensity-matched analysis.
Schlotter F, Miura M, Kresoja KP, Alushi B, Alessandrini H, Attinger-Toller A, Besler C, Biasco L, Braun D, Brochet E, Connelly KA, de Bruijn S, Denti P, Estevez-Loureiro R, Fam N, Gavazzoni M, Himbert D, Ho EC, Juliard JM, Kalbacher D, Kaple R, Kreidel F, Latib A, Lubos E, Ludwig S, Mehr M, Monivas V, Nazif TM, Nickenig G, Pedrazzini G, Pozzoli A, Praz F, Puri R, Rodés-Cabau J, Rommel KP, Schäfer U, Schofer J, Sievert H, Tang GHL, Thiele H, Unterhuber M, Vahanian A, von Bardeleben RS, von Roeder M, Webb JG, Weber M, Wild MG, Windecker S, Zuber M, Hausleiter J, Maisano F, Leon MB, Hahn RT, Lauten A, Taramasso M, Lurz P.
EuroIntervention. 2021 Jul 20; 17(4):e343-e352. - 2-Year Outcomes for Transcatheter Repair in Patients With Mitral Regurgitation From the CLASP Study.
Szerlip M, Spargias KS, Makkar R, Kar S, Kipperman RM, O'Neill WW, Ng MKC, Smith RL, Fam NP, Rinaldi MJ, Raffel OC, Walters DL, Levisay J, Montorfano M, Latib A, Carroll JD, Nickenig G, Windecker S, Marcoff L, Cohen GN, Schäfer U, Webb JG, Lim DS.
JACC Cardiovasc Interv. 2021 Jul 26; 14(14):1538-1548. - Transcatheter Tricuspid Valve Intervention in Patients With Previous Left Valve Surgery.
Muntané-Carol G, Taramasso M, Miura M, Gavazzoni M, Pozzoli A, Alessandrini H, Latib A, Attinger-Toller A, Biasco L, Braun D, Brochet E, Connelly KA, Sievert H, Denti P, Lubos E, Ludwig S, Kalbacher D, Estevez-Loureiro R, Fam N, Frerker C, Ho E, Juliard JM, Kaple R, Kodali S, Kreidel F, Harr C, Lauten A, Lurz J, Kresoja KP, Monivas V, Mehr M, Nazif T, Nickening G, Pedrazzini G, Philippon F, Praz F, Puri R, Schäfer U, Schofer J, Tang GHL, Khattab AA, Andreas M, Russo M, Thiele H, Unterhuber M, Himbert D, Urena M, von Bardeleben RS, Webb JG, Weber M, Winkel M, Zuber M, Hausleiter J, Lurz P, Maisano F, Leon MB, Hahn RT, Rodés-Cabau J.
Can J Cardiol. 2021 Jul; 37(7):1094-1102. - Procedural and clinical outcomes of type 0 versus type 1 bicuspid aortic valve stenosis undergoing trans-catheter valve replacement with new generation devices: Insight from the BEAT international collaborative registry.
Ielasi A, Moscarella E, Mangieri A, Giannini F, Tchetchè D, Kim WK, Sinning JM, Landes U, Kornowski R, De Backer O, Nickenig G, De Biase C, Søndergaard L, De Marco F, Bedogni F, Ancona M, Montorfano M, Regazzoli D, Stefanini G, Toggweiler S, Tamburino C, Immè S, Tarantini G, Sievert H, Schäfer U, Kempfert J, Wöehrle J, Latib A, Calabrò P, Medda M, Tespili M, Colombo A.
Int J Cardiol. 2021 Feb 15; 325:109-114. - Spontaneous echo contrast, left atrial appendage thrombus and stroke in patients undergoing transcatheter aortic valve implantation.
Linder M, Voigtländer L, Schneeberger Y, Bhadra OD, Grundmann D, Demal T, Goßling A, Ludwig S, Schaefer A, Waldschmidt L, Schirmer J, Reichenspurner H, Blankenberg S, Schäfer U, Westermann D, Schofer N, Conradi L, Seiffert M.
EuroIntervention. 2021 Jan 20; 16(13):1114-1122. - Predictors of high residual gradient after transcatheter aortic valve replacement in bicuspid aortic valve stenosis.
Bugani G, Pagnesi M, Tchetchè D, Kim WK, Khokhar A, Sinning JM, Landes U, Kornowski R, Codner P, De Backer O, Nickenig G, Ielasi A, De Biase C, Søndergaard L, De Marco F, Ancona M, Montorfano M, Regazzoli D, Stefanini G, Toggweiler S, Tamburino C, Immè S, Tarantini G, Sievert H, Schäfer U, Kempfert J, Wöehrle J, Tespili M, Laricchia A, Latib A, Giannini F, Colombo A, Mangieri
Clin Res Cardiol. 2021 May; 110(5):667-675. - Transapical transcatheter mitral valve implantation in patients with prior aortic valve replacement: a feasibility report.
Taramasso M, Sorajja P, Dahle G, Dumonteil N, Schäfer U, Modine T, Overtchouk P, Coisne A, Nickenig G, Babaliaros V, Khattab AA, Ludwig S, Conradi L, Collaborators.
EuroIntervention. 2021 Jun 25; 17(3):257-259.# - TAVI in Patients with Mitral Annular Calcification and/or Mitral Stenosis.
Schaefer A, Sarwari H, Schofer N, Schneeberger Y, Westermann D, Schoen G, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L.
Thorac Cardiovasc Surg. 2021 Aug; 69(5):428-436. - Tricuspid valve repair with the Cardioband system: two-year outcomes of the multicentre, prospective TRI-REPAIR study.
Nickenig G, Weber M, Schüler R, Hausleiter J, Nabauer M, von Bardeleben RS, Sotiriou E, Schäfer U, Deuschl F, Alessandrini H, Kreidel F, Juliard JM, Brochet E, Latib A, Montorfano M, Agricola E, Baldus S, Friedrichs KP, Deo SH, Gilmore SY, Feldman T, Hahn RT, Maisano F.
EuroIntervention. 2021 Feb 5; 16(15):e1264-e1271. - Mechanical ventilation and mortality among 223 critically ill patients with COVID-19 – a multicentric study in Germany.
Roedl K, Jarczak D, Thasler L, Bachmann M, Schulte F, Bein B, Weber C F, Schäfer U, Veit C, Hauber H-P, Kopp S, Sydow K, de Weerth A, Bota M, Schreiber R, Detsch O, Rogmann J-P, Frings D, Sensen B, Burdelski C, Boenisch O, Nierhaus A, de Heer G, Kluge S.
Aust Crit Care. 2021 Mar; 34(2):167-175 - 1-Year Outcomes for Transcatheter Repair in Patients With Mitral Regurgitation From the CLASP Study.
Webb JG, Hensey M, Szerlip M, Schäfer U, Cohen GN, Kar S, Makkar R, Kipperman RM, Spargias K, O'Neill WW, Ng MKC, Fam NP, Rinaldi MJ, Smith RL, Walters DL, Raffel CO, Levisay J, Latib A, Montorfano M, Marcoff L, Shrivastava M, Boone R, Gilmore S, Feldman TE, Lim DS.
JACC Cardiovasc Interv. 2020: 13(20):2344-2357. - Two-year Outcomes with the Cardioband Tricuspid System from the Multicentre, Prospective TRI-REPAIR Study.
Nickenig G, Weber M, Schüler R, Hausleiter J, Nabauer M, von Bardeleben RS, Sotiriou E, Schäfer U, Deuschl F, Alessandrini H, Kreidel F, Juliard JM, Brochet E, Latib A, Montorfano M, Agricola E, Baldus S, Friedrichs KP, Deo SH, Gilmore SY, Feldman T, Hahn RT, Maisano F.
EuroIntervention. 2020: EIJ-D-20-01107. - Impact of Massive or Torrential Tricuspid Regurgitation in Patients Undergoing Transcatheter Tricuspid Valve Intervention.
Miura M, Alessandrini H, Alkhodair A, Attinger-Toller A, Biasco L, Lurz P, Braun D, Brochet E, Connelly KA, de Bruijn S, Denti P, Deuschl F, Estevez-Loureiro R, Fam N, Frerker C, Gavazzoni M, Hausleiter J, Himbert D, Ho E, Juliard JM, Kaple R, Besler C, Kodali S, Kreidel F, Kuck KH, Latib A, Lauten A, Monivas V, Mehr M, Muntané-Carol G, Nazif T, Nickenig G, Pedrazzini G, Philippon F, Pozzoli A, Praz F, Puri R, Rodés-Cabau J, Schäfer U, Schofer J, Sievert H, Tang GHL, Thiele H, Rommel KP, Vahanian A, Von Bardeleben RS, Webb JG, Weber M, Windecker S, Winkel M, Zuber M, Leon MB, Maisano F, Hahn RT, Taramasso M; TriValve Investigators.
JACC Cardiovasc Interv. 2020: 13(17):1999-2009. - Balloon Versus Self-Expandable Valve for the Treatment of Bicuspid Aortic Valve Stenosis: Insights From the BEAT International Collaborative Registrys.
Mangieri A, Tchetchè D, Kim WK, Pagnesi M, Sinning JM, Landes U, Kornowski R, De Backer O, Nickenig G, Ielasi A, De Biase C, Søndergaard L, De Marco F, Montorfano M, Chiarito M, Regazzoli D, Stefanini G, Presbitero P, Toggweiler S, Tamburino C, Immè S, Tarantini G, Sievert H, Schäfer U, Kempfert J, Wöehrle J, Gallo F, Laricchia A, Latib A, Giannini F, Colombo A.
Circ Cardiovasc Interv. 2020: 13(7):e008714. - Screening for transcatheter mitral valve replacement: a decision tree algorithm.
Ludwig S, Ruebsamen N, Deuschl F, Schofer N, Kalbacher D, Schaefer A, Koell B, Westermann D, Reichenspurner H, Blankenberg S, Schäfer U, Conradi L, Lubos E.
EuroIntervention. 2020: 16(3):251-258. - Prognostic Impact of Underweight (Body Mass Index <20 kg/m2) in Patients With Severe Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation or Surgical Aortic Valve Replacement (from the German Aortic Valve Registry [GARY]).
Voigtländer L, Twerenbold R, Schäfer U, Conradi L, Balaban Ü, Bekeredjian R, Ensminger S, Walther T, Beckmann A, Frerker C, Bauer T, Hamm C, Möllmann H, Bleiziffer S; GARY Executive Board.
Am J Cardiol. 2020: 129:79-86. - Impact of device landing zone calcification patterns on paravalvular regurgitation after transcatheter aortic valve replacement with different next-generation devices.
Mauri V, Frohn T, Deuschl F, Mohemed K, Kuhr K, Reimann A, Körber MI, Schofer N, Adam M, Friedrichs K, Kuhn EW, Scholtz S, Rudolph V, Wahlers TCW, Baldus S, Mader N, Schäfer U, Rudolph TK.
Open Heart. 2020: 7(1):e001164. - Value of Echocardiographic Right Ventricular and Pulmonary Pressure Assessment in Predicting Transcatheter Tricuspid Repair Outcome.
Karam N, Mehr M, Taramasso M, Besler C, Ruf T, Connelly KA, Weber M, Yzeiraj E, Schiavi D, Mangieri A, Vaskelyte L, Alessandrini H, Deuschl F, Brugger N, Ahmad H, Ho E, Biasco L, Orban M, Deseive S, Braun D, Gavazzoni M, Rommel KP, Pozzoli A, Frerker C, Näbauer M, Massberg S, Pedrazzini G, Tang GHL, Windecker S, Schäfer U, Kuck KH, Sievert H, Denti P, Latib A, Schofer J, Nickenig G, Fam N, von Bardeleben S, Lurz P, Maisano F, Hausleiter J.
JACC Cardiovasc Interv. 2020: 13(10):1251-1261. - 5-Year Outcomes After TAVR With Balloon-Expandable Versus Self-Expanding Valves: Results From the CHOICE Randomized Clinical Trial.
Abdel-Wahab M, Landt M, Neumann FJ, Massberg S, Frerker C, Kurz T, Kaur J, Toelg R, Sachse S, Jochheim D, Schäfer U, El-Mawardy M, Robinson DR, Richardt G; CHOICE Investigators.
JACC Cardiovasc Interv. 2020: 11; 13(9):1071-1082. - TAVR for low-flow, low-gradient aortic stenosis: Prognostic impact of aortic valve calcification.
Ludwig S, Goßling A, Waldschmidt L, Linder M, Bhadra OD, Voigtländer L, Schäfer A, Deuschl F, Schirmer J, Reichenspurner H, Blankenberg S, Schäfer U, Westermann D, Seiffert M, Conradi L, Schofer N.
Am Heart J. 2020: 225:138-148. - The impact of residual mitral regurgitation after MitraClip therapy in functional mitral regurgitation.
Reichart D, Kalbacher D, Rübsamen N, Tigges E, Thomas C, Schirmer J, Reichenspurner H, Blankenberg S, Conradi L, Schäfer U, Lubos E.
Eur J Heart Fail. 2020 Apr 8. doi: 10.1002/ejhf.1774. Online ahead of print. - Transcatheter aortic valve implantation with the ACURATE neo valve: indications, procedural aspects and clinical outcomes.
Kim WK, Hengstenberg C, Hilker M, Schäfer U, Rudolph TK, Toggweiler S, Rück A, Søndergaard L, Conradi L, Hamm C, Walther T, Möllmann H; Collaborators.
EuroIntervention. 2020: 15(18):e1571-e1579. - Chimney Stenting for Coronary Occlusion During TAVR: Insights From the Chimney Registry.
Mercanti F, Rosseel L, Neylon A, Bagur R, Sinning JM, Nickenig G, Grube E, Hildick-Smith D, Tavano D, Wolf A, Colonna G, Latib A, Mitomo S, Petronio AS, Angelillis M, Tchétché D, De Biase C, Adamo M, Nejjari M, Digne F, Schäfer U, Amabile N, Achkouty G, Makkar RR, Yoon SH, Finkelstein A, Dvir D, Jones T, Chevalier B, Lefevre T, Piazza N, Mylotte D.
JACC Cardiovasc Interv. 2020: 13(6):751-761. - TAVI in Patients with Mitral Annular Calcification and/or Mitral Stenosis.
Schaefer A, Sarwari H, Schofer N, Schneeberger Y, Westermann D, Schoen G, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L.
Thorac Cardiovasc Surg. 2020 Mar 1. doi: 10.1055/s-0039-1700966. Online ahead of print. - Impact of Predilatation Prior to Transcatheter Aortic Valve Implantation With the Self-Expanding Acurate neo Device (from the Multicenter NEOPRO Registry).
Pagnesi M, Kim WK, Conradi L, Barbanti M, Stefanini GG, Schofer J, Hildick-Smith D, Pilgrim T, Abizaid A, Zweiker D, Testa L, Taramasso M, Wolf A, Webb JG, Sedaghat A, Van der Heyden JAS, Ziviello F, MacCarthy P, Hamm CW, Bhadra OD, Schäfer U, Costa G, Tamburino C, Cannata F, Reimers B, Eitan A, Alsanjari O, Asami M, Windecker S, Siqueira D, Schmidt A, Bianchi G, Bedogni F, Saccocci M, Maisano F, Jensen CJ, Naber CK, Alenezi A, Wood DA, Sinning JM, Brouwer J, Tzalamouras V, Van Mieghem NM, Colombo A, Latib A.
Am J Cardiol. 2020: 125(9):1369-1377. - Combined Tricuspid and Mitral Versus Isolated Mitral Valve Repair for Severe MR and TR: An Analysis From the TriValve and TRAMI Registries.
Mehr M, Karam N, Taramasso M, Ouarrak T, Schneider S, Lurz P, von Bardeleben RS, Fam N, Pozzoli A, Lubos E, Boekstegers P, Schillinger W, Plicht B, Eggebrecht H, Baldus S, Senges J, Maisano F, Hausleiter J; TriValve and TRAMI Investigators.
JACC Cardiovasc Interv. 2020: 13(5):543-550. - Outcomes of TTVI in Patients With Pacemaker or Defibrillator Leads: Data From the TriValve Registry.
Taramasso M, Gavazzoni M, Pozzoli A, Alessandrini H, Latib A, Attinger-Toller A, Biasco L, Braun D, Brochet E, Connelly KA, de Bruijn S, Denti P, Deuschl F, Estevez-Louriero R, Fam N, Frerker C, Ho E, Juliard JM, Kaple R, Kodali S, Kreidel F, Kuck KH, Lauten A, Lurz J, Monivas V, Mehr M, Nazif T, Nickening G, Pedrazzini G, Praz F, Puri R, Rodés-Cabau J, Schäfer U, Schofer J, Sievert H, Tang GHL, Khattab AA, Thiele H, Unterhuber M, Vahanian A, Von Bardeleben RS, Webb JG, Weber M, Windecker S, Winkel M, Zuber M, Hausleiter J, Lurz P, Maisano F, Leon MB, Hahn RT.
JACC Cardiovasc Interv. 2020:13(5):554-564. - Mitral regurgitation severity predicts one-year therapeutic benefit of Tendyne transcatheter mitral valve implantation.
Badhwar V, Sorajja P, Duncan A, Thourani V, Schäfer U, Grayburn P, Dumonteil N, Babaliaros V, Garatti A, Leipsic J, Chuang M, Blanke P, Muller D.
EuroIntervention. 2019: 15(12):e1065-e1071. - Clinical outcomes after TAVR with heparin or bivalirudin as periprocedural anticoagulation in patients with and without peripheral arterial disease: Results from the BRAVO-3 randomized trial.
Zilberszac R, Chandiramani R, Hengstenberg C, Sartori S, Cao D, Chandrasekhar J, Schäfer U, Tchetche D, Violini R, Jeger R, Van Belle E, Boekstegers P, Hambrecht R, Tron C, Dumenteil N, Linke A, Ten Berg JM, Deliargyris EN, Anthopoulos P, Mehran R, Dangas G.
Catheter Cardiovasc Interv. 2020: 96(3):E377-E386. - Transcatheter aortic valve implantation versus surgical aortic valve replacement in low-risk patients: a propensity score-matched analysis.
Schaefer A, Schofer N, Goßling A, Seiffert M, Schirmer J, Deuschl F, Schneeberger Y, Voigtländer L, Detter C, Schäfer U, Blankenberg S, Reichenspurner H, Conradi L, Westermann D.
Eur J Cardiothorac Surg. 2019: 56(6):1131-1139. - Impact f pre- and post-procedural renal dysfunction on long-term outcomes in patients undergoing MitraClip implantation: A retrospective analysis from two German high-volume centres.
Kalbacher D, Daubmann A, Tigges E, Hünlich M, Wiese S, Conradi L, Schirmer J, Beuthner BE, Reichenspurner H, Wegscheider K, Danner BC, Tichelbäcker T, Hasenfuß G, Schäfer U, Blankenberg S, Puls M, Schillinger W, Lubos E.
Int J Cardiol. 2020: 300:87-92. - A Controlled Trial of Rivaroxaban after Transcatheter Aortic-Valve Replacement.
Dangas GD, Tijssen JGP, Wöhrle J, Søndergaard L, Gilard M, Möllmann H, Makkar RR, Herrmann HC, Giustino G, Baldus S, De Backer O, Guimarães AHC, Gullestad L, Kini A, von Lewinski D, Mack M, Moreno R, Schäfer U, Seeger J, Tchétché D, Thomitzek K, Valgimigli M, Vranckx P, Welsh RC, Wildgoose P, Volkl AA, Zazula A, van Amsterdam RGM, Mehran R, Windecker S; GALILEO Investigators.
N Engl J Med. 2020: 382(2):120-129. - Safety and Performance Outcomes of a Self-Expanding Transcatheter Aortic Heart Valve: The BIOVALVE Trials.
Schäfer U, Kempfert J, Verheye S, Maisano F, Thiele H, Landt M, Haude M, Rudolph TK, Ince H, Kische S, Treede H, Tonino P, Conradi L.
JACC Cardiovasc Interv. 2020: 13(2):157-166. - IIncidence and outcome of peri-procedural transcatheter heart valve embolization and migration: the TRAVEL registry (TranscatheteR HeArt Valve EmboLization and Migration).
Kim WK, Schäfer U, Tchetche D, Nef H, Arnold M, Avanzas P, Rudolph T, Scholtz S, Barbanti M, Kempfert J, Mangieri A, Lauten A, Frerker C, Yoon SH, Holzamer A, Praz F, De Backer O, Toggweiler S, Blumenstein J, Purita P, Tarantini G, Thilo C, Wolf A, Husser O, Pellegrini C, Burgdorf C, Antolin RAH, Díaz VAJ, Liebetrau C, Schofer N, Möllmann H, Eggebrecht H, Sondergaard L, Walther T, Pilgrim T, Hilker M, Makkar R, Unbehaun A, Börgermann J, Moris C, Achenbach S, Dörr O, Brochado B, Conradi L, Hamm CW.
Eur Heart J. 2019: 40(38):3156-3165. - Thirty-day outcomes of a novel transcatheter heart valve to treat degenerated surgical valves: the VIVALL multicentre, single-arm, pilot study.
Schäfer U, Butter C, Landt M, Frerker C, Treede H, Schirmer J, Koban C, Allali A, Schmidt T, Charitos E, Conradi L.
EuroIntervention. 2019: 15(9):e757-e763. - Transcatheter Versus Medical Treatment of Patients With Symptomatic Severe Tricuspid Regurgitation.
Taramasso M, Benfari G, van der Bijl P, Alessandrini H, Attinger-Toller A, Biasco L, Lurz P, Braun D, Brochet E, Connelly KA, de Bruijn S, Denti P, Deuschl F, Estevez-Loureiro R, Fam N, Frerker C, Gavazzoni M, Hausleiter J, Ho E, Juliard JM, Kaple R, Besler C, Kodali S, Kreidel F, Kuck KH, Latib A, Lauten A, Monivas V, Mehr M, Muntané-Carol G, Nazif T, Nickening G, Pedrazzini G, Philippon F, Pozzoli A, Praz F, Puri R, Rodés-Cabau J, Schäfer U, Schofer J, Sievert H, Tang GHL, Thiele H, Topilsky Y, Rommel KP, Delgado V, Vahanian A, Von Bardeleben RS, Webb JG, Weber M, Windecker S, Winkel M, Zuber M, Leon MB, Hahn RT, Bax JJ, Enriquez-Sarano M, Maisano F.
J Am Coll Cardiol. 2019: 74(24):2998-3008. - Transcatheter Valve SELECTion in Patients With Right Bundle Branch Block and Impact on Pacemaker Implantations.
Husser O, Pellegrini C, Kim WK, Holzamer A, Pilgrim T, Toggweiler S, Schäfer U, Blumenstein J, Deuschl F, Rheude T, Joner M, Hilker M, Hengstenberg C, Möllmann H.
JACC Cardiovasc Interv. 2019: 12(18):1781-1793. - Novel Transcatheter Mitral Valve Prosthesis for Patients With Severe Mitral Annular Calcification.
Sorajja P, Gössl M, Babaliaros V, Rizik D, Conradi L, Bae R, Burke RF, Schäfer U, Lisko JC, Riley RD, Guyton R, Dumonteil N, Berthoumieu P, Tchetche D, Blanke P, Cavalcante JL, Sun B.
J Am Coll Cardiol. 2019: 74(11):1431-1440. - Current Generation Balloon-Expandable Transcatheter Valve Positioning Strategies During Aortic Valve-in-Valve Procedures and Clinical Outcomes.
Simonato M, Webb J, Bleiziffer S, Abdel-Wahab M, Wood D, Seiffert M, Schäfer U, Wöhrle J, Jochheim D, Woitek F, Latib A, Barbanti M, Spargias K, Kodali S, Jones T, Tchetche D, Coutinho R, Napodano M, Garcia S, Veulemans V, Siqueira D, Windecker S, Cerillo A, Kempfert J, Agrifoglio M, Bonaros N, Schoels W, Baumbach H, Schofer J, Gaia DF, Dvir D.
JACC Cardiovasc Interv. 2019: 12(16):1606-1617. - 1-Year Outcomes After Edge-to-Edge Valve Repair for Symptomatic Tricuspid Regurgitation: Results From the TriValve Registry.
Mehr M, Taramasso M, Besler C, Ruf T, Connelly KA, Weber M, Yzeiraj E, Schiavi D, Mangieri A, Vaskelyte L, Alessandrini H, Deuschl F, Brugger N, Ahmad H, Biasco L, Orban M, Deseive S, Braun D, Rommel KP, Pozzoli A, Frerker C, Näbauer M, Massberg S, Pedrazzini G, Tang GHL, Windecker S, Schäfer U, Kuck KH, Sievert H, Denti P, Latib A, Schofer J, Nickenig G, Fam N, von Bardeleben S, Lurz P, Maisano F, Hausleiter J.
JACC Cardiovasc Interv. 2019: 12(15):1451-1461. - Transcatheter Valve Repair for Patients With Mitral Regurgitation: 30-Day Results of the CLASP Study.
Lim DS, Kar S, Spargias K, Kipperman RM, O'Neill WW, Ng MKC, Fam NP, Walters DL, Webb JG, Smith RL, Rinaldi MJ, Latib A, Cohen GN, Schäfer U, Marcoff L, Vandrangi P, Verta P, Feldman TE.
JACC Cardiovasc Interv. 2019: 12(14):1369-1378. - TAVR for Failed Surgical Aortic Bioprostheses Using a Self-Expanding Device: 1-Year Results From the Prospective VIVA Postmarket Study.
Tchétché D, Chevalier B, Holzhey D, Harnath A, Schäfer U, Teiger E, Manigold T, Modine T, Souteyrand G, Champagnac D, Oh JK, Li S, Verhoye JP, Kornowski R; VIVA Investigators.
JACC Cardiovasc Interv. 2019: 12(10):923-932. - Impact of percutaneous closure device type on vascular and bleeding complications after TAVR: A post hoc analysis from the BRAVO-3 randomized trial.
Power D, Schäfer U, Guedeney P, Claessen BE, Sartori S, Sorrentino S, Lefèvre T, Kupatt C, Tchetche D, Dumonteil N, Webb JG, Colombo A, Windecker S, Ten Berg JM, Hildick-Smith D, Boekstegers P, Linke A, Tron C, Van Belle E, Asgar AW, Jeger R, Sardella G, Hink U, Husser O, Grube E, Lechthaler I, Wijngaard P, Anthopoulos P, Deliargyris EN, Bernstein D, Hengstenberg C, Mehran R, Dangas GD.
Catheter Cardiovasc Interv. 2019: 93(7):1374-1381. - Transcatheter aortic valve-in-valve implantation in degenerative rapid deployment bioprostheses.
Landes U, Dvir D, Schoels W, Tron C, Ensminger S, Simonato M, Schäfer U, Bunc M, Aldea GS, Cerillo A, Windecker S, Marzocchi A, Andreas M, Amabile N, Webb J, Kornowski R.
EuroIntervention. 2019: 15(1):37-43. - 6-Month Outcomes of Tricuspid Valve Reconstruction for Patients With Severe Tricuspid Regurgitation.
Nickenig G, Weber M, Schueler R, Hausleiter J, Näbauer M, von Bardeleben RS, Sotiriou E, Schäfer U, Deuschl F, Kuck KH, Kreidel F, Juliard JM, Brochet E, Latib A, Agricola E, Baldus S, Friedrichs K, Vandrangi P, Verta P, Hahn RT, Maisano F.
J Am Coll Cardiol. 2019: 73(15):1905-1915. - Can We Predict Failure of Mitral Valve Repair?
Gasser S, von Stumm M, Sinning C, Schäfer U, Reichenspurner H, Girdauskas E.
J Clin Med. 2019: 8(4):526. - 1-Year Outcomes of the CENTERA-EU Trial Assessing a Novel Self-Expanding Transcatheter Heart Valve.
Tchétché D, Windecker S, Kasel AM, Schäfer U, Worthley S, Linke A, Abdel-Wahab M, Le Breton H, Søndergaard L, Spence MS, Petronio S, Baumgartner H, Hovorka T, Blanke P, Reichenspurner H.
JACC Cardiovasc Interv. 2019: 12(7):673-680. - Prosthesis-patient mismatch after transcatheter aortic valve implantation: prevalence and prognostic impact with respect to baseline left ventricular function.
Schofer N, Deuschl F, Rübsamen N, Skibowski J, Seiffert M, Voigtländer L, Schaefer A, Schneeberger Y, Schirmer J, Reichenspurner H, Blankenberg S, Conradi L, Schäfer U.
EuroIntervention. 2019: 14(16):1648-1655. - Transcatheter Aortic Valve Replacement With Next-Generation Self-Expanding Devices: A Multicenter, Retrospective, Propensity-Matched Comparison of Evolut PRO Versus Acurate neo Transcatheter Heart Valves.
Pagnesi M, Kim WK, Conradi L, Barbanti M, Stefanini GG, Zeus T, Pilgrim T, Schofer J, Zweiker D, Testa L, Taramasso M, Hildick-Smith D, Abizaid A, Wolf A, Van Mieghem NM, Sedaghat A, Wöhrle J, Khogali S, Van der Heyden JAS, Webb JG, Estévez-Loureiro R, Mylotte D, MacCarthy P, Brugaletta S, Hamm CW, Bhadra OD, Schäfer U, Costa G, Tamburino C, Cannata F, Reimers B, Veulemans V, Asami M, Windecker S, Eitan A, Schmidt A, Bianchi G, Bedogni F, Saccocci M, Maisano F, Alsanjari O, Siqueira D, Jensen CJ, Naber CK, Ziviello F, Sinning JM, Seeger J, Rottbauer W, Brouwer J, Alenezi A, Wood DA, Tzalamouras V, Regueiro A, Colombo A, Latib A.
JACC Cardiovasc Interv. 2019: 12(5):433-443. - Outcomes of transcatheter mitral valve replacement for degenerated bioprostheses, failed annuloplasty rings, and mitral annular calcification.
Yoon SH, Whisenant BK, Bleiziffer S, Delgado V, Dhoble A, Schofer N, Eschenbach L, Bansal E, Murdoch DJ, Ancona M, Schmidt T, Yzeiraj E, Vincent F, Niikura H, Kim WK, Asami M, Unbehaun A, Hirji S, Fujita B, Silaschi M, Tang GHL, Kuwata S, Wong SC, Frangieh AH, Barker CM, Davies JE, Lauten A, Deuschl F, Nombela-Franco L, Rampat R, Nicz PFG, Masson JB, Wijeysundera HC, Sievert H, Blackman DJ, Gutierrez-Ibanes E, Sugiyama D, Chakravarty T, Hildick-Smith D, de Brito FS Jr, Jensen C, Jung C, Smalling RW, Arnold M, Redwood S, Kasel AM, Maisano F, Treede H, Ensminger SM, Kar S, Kaneko T, Pilgrim T, Sorajja P, Van Belle E, Prendergast BD, Bapat V, Modine T, Schofer J, Frerker C, Kempfert J, Attizzani GF, Latib A, Schäfer U, Webb JG, Bax JJ, Makkar RR.
Eur Heart J. 2019: 40(5):441-451. - Outcomes After Current Transcatheter Tricuspid Valve Intervention: Mid-Term Results From the International TriValve Registry.
Taramasso M, Alessandrini H, Latib A, Asami M, Attinger-Toller A, Biasco L, Braun D, Brochet E, Connelly KA, Denti P, Deuschl F, Englmeier A, Fam N, Frerker C, Hausleiter J, Himbert D, Ho EC, Juliard JM, Kaple R, Kreidel F, Kuck KH, Ancona M, Lauten A, Lurz P, Mehr M, Nazif T, Nickening G, Pedrazzini G, Pozzoli A, Praz F, Puri R, Rodés-Cabau J, Schäfer U, Schofer J, Sievert H, Sievert K, Tang GHL, Tanner FC, Vahanian A, Webb JG, Windecker S, Yzeiray E, Zuber M, Maisano F, Leon MB, Hahn RT.
JACC Cardiovasc Interv. 2019: 12(2):155-165. - Transaxillary transcatheter aortic valve implantation utilizing a novel vascular closure device with resorbable collagen material: a feasibility study.
Schaefer A, Schirmer J, Schofer N, Schneeberger Y, Deuschl F, Blankenberg S, Reichenspurner H, Conradi L, Schäfer U.
Clin Res Cardiol. 2019: 108(7):779-786. - "Tailored" endovascular pulmonary valve and root replacement for rupture of a dilated homograft.
Müller GC, Sinning C, Zengin-Sahm E, Stark V, Mir TS, Rickers C, Kozlik-Feldmann R, Kölbel T, Schäfer U.
Cardiovasc Diagn Ther. 2018: 8(6):820-824. - Early commercial experience from transcatheter aortic valve implantation using the Portico™ bioprosthetic valve: 30-day outcomes in the multicentre PORTICO-1 study.
Maisano F, Worthley S, Rodés-Cabau J, Linke AH, Fichtlscherer S, Schäfer U, Makkar RR, Fontana G, Asch FM, Søndergaard L.
EuroIntervention. 2018: 20; 14(8):886-893. - Transcatheter aortic valve implantation utilizing a non-occlusive balloon for predilatation.
Schneeberger Y, Schaefer A, Schofer N, Silaschi M, Deuschl F, Blankenberg S, Reichenspurner H, Treede H, Schäfer U, Charitos EI, Conradi L.
Int J Cardiol. 2019: 15; 275:65-69. - Insights from eight years of adoption experience of transcatheter mitral valve repair in Germany: observed utilisation patterns and impact on overall mitral valve procedure volumes.
Schaefer A, Lubos E, Pietzsch JB, Pietzsch M, Weber S, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L.
EuroIntervention. 2018: 14(9):e981-e987. - Transcatheter Mitral Valve Replacement in Patients With Previous Aortic Valve Replacement.
Cheung A, Webb J, Schäfer U, Moss R, Deuschl FG, Conradi L, Denti P, Latib A, Kiaii B, Bagur R, Ferrari E, Moccetti M, Biasco L, Blanke P, Ben-Gal Y, Banai S.
Circ Cardiovasc Interv. 2018: 11(10):e006412. - Prospective multicentre evaluation of a novel, low-profile transapical delivery system for self-expandable transcatheter aortic valve implantation: 6-month outcomes.
Conradi L, Hilker M, Kempfert J, Börgermann J, Treede H, Holzhey DM, Schröfel H, Kim WK, Schäfer U, Walther T.
Eur J Cardiothorac Surg. 2018: 54(4):762-767. - Transcatheter Aortic Valve Replacement With a Repositionable Self-Expanding Prosthesis: The PORTICO-I Trial 1-Year Outcomes.
Søndergaard L, Rodés-Cabau J, Hans-Peter Linke A, Fichtlscherer S, Schäfer U, Kuck KH, Kempfert J, Arzamendi D, Bedogni F, Asch FM, Worthley S, Maisano F.
J Am Coll Cardiol. 2018: 72(23 Pt A):2859-2867. - Valve-in-valve-in-valve: Balloon expandable transcatheter heart valve in failing self-expandable transcatheter heart valve in deteriorated surgical bioprosthesis.
Schaefer A, Deuschl F, Conradi L, Schäfer U.
Catheter Cardiovasc Interv. 2018: 92(7):E481-E485. - Incidence of new-onset left bundle branch block and predictors of new permanent pacemaker following transcatheter aortic valve replacement with the Portico™ valve.
Walther T, Manoharan G, Linke A, Möllmann H, Holzhey D, Worthley SG, Kim WK, Schäfer U.
Eur J Cardiothorac Surg. 2018: 54(3):467-474. - Long-term outcome, survival and predictors of mortality after MitraClip therapy: Results from the German Transcatheter Mitral Valve Interventions (TRAMI) registry.
Kalbacher D, Schäfer U, V Bardeleben RS, Eggebrecht H, Sievert H, Nickenig G, Butter C, May AE, Bekeredjian R, Ouarrak T, Kuck KH, Plicht B, Zahn R, Baldus S, Ince H, Schillinger W, Boekstegers P, Senges J, Lubos E.
Int J Cardiol. 2019: 277:35-41. - Computed tomography-based oversizing and incidence of paravalvular aortic regurgitation and permanent pacemaker implantation with a new-generation self-expanding transcatheter heart valve.
Kim U, Blanke P, Windecker S, Kasel AM, Schäfer U, Walters D, Linke A, Le Breton H, Schymik G, Spence MS, Søndergaard L, Abdel-Wahab M, Worthley S, Tchétché D, Reichenspurner H, Ohana M, Sellers SL, Leipsic JA.
EuroIntervention. 2018: 14(5):e511-e518. - The SAVI-TF Registry: 1-Year Outcomes of the European Post-Market Registry Using the ACURATE neo Transcatheter Heart Valve Under Real-World Conditions in 1,000 Patients.
Kim WK, Hengstenberg C, Hilker M, Kerber S, Schäfer U, Rudolph T, Linke A, Franz N, Kuntze T, Nef H, Kappert U, Zembala MO, Toggweiler S, Walther T, Möllmann H.
JACC Cardiovasc Interv. 2018: 11(14):1368-1374. - Usefulness of Transcatheter Aortic Valve Implantation for Treatment of Pure Native Aortic Valve Regurgitation.
De Backer O, Pilgrim T, Simonato M, Mackensen GB, Fiorina C, Veulemanns V, Cerillo A, Schofer J, Amabile N, Achkouty G, Schäfer U, Deutsch MA, Sinning JM, Rahman MS, Sawaya FJ, Hildick-Smith D, Hernandez JM, Kim WK, Lefevre T, Seiffert M, Bleiziffer S, Petronio AS, Van Mieghem N, Taramasso M, Søndergaard L, Windecker S, Latib A, Dvir D.
Am J Cardiol. 2018: 122(6):1028-1035. - Comparative analysis of balloon- versus mechanically-expandable transcatheter heart valves considering landing zone calcification
Schofer N, Deuschl F, Schön G, Seiffert M, Linder M, Schäfer A, Schirmer J, Lubos E, Treede H, Reichenspurner H, Blankenberg S, Conradi L, Schäfer U.
Journal of Cardiology 2018: 71(6): 540-546 - Transcatheter aortic valve implantation with the 34 mm self-expanding CoreValve Evolut R: initial experience in 101 patients from a multicentre registry.
Kuhn C, Frerker C, Meyer AK, Kurz T, Schäfer U, Deuschl F, Abdel-Wahab M, Schewel D, Elghalban A, Kuck KH, Frey N, Frank D.
EuroIntervention. 2018: 14(3):e301-e305. - Outcomes with a latest generation self-expandable, intra-annular, re-sheathable transcatheter heart valve system: analysis of patients with impaired left ventricular function and determinants for pacemaker implantation.
Schaefer A, Neumann N, Linder M, Schofer N, Schneeberger Y, Deuschl F, Schoen G, Blankenberg S, Reichenspurner H, Conradi L, Schäfer U.
Clin Res Cardiol. 2018: 107(10):914-923. - In vitro hydrodynamic and acute clinical performance of a novel self-expanding transcatheter heart valve in various surgical bioprostheses.
Sedaghat A, Sinning JM, Werner N, Nickenig G, Conradi L, Toggweiler S, Schäfer U.
EuroIntervention. 2018: 13(17):2014-2017 - Predictors of paravalvular regurgitation and permanent pacemaker implantation after TAVR with a next-generation self-expanding device.
Mauri V, Deuschl F, Frohn T, Schofer N, Linder M, Kuhn E, Schaefer A, Rudolph V, Madershahian N, Conradi L, Rudolph TK, Schäfer U.
Clin Res Cardiol. 2018: 107(8):688-697. - Distinct Hemodynamic Changes After Interventional Mitral Valve Edge-to-Edge Repair in Different Phenotypes of Heart Failure: An Integrated Hemodynamic Analysis.
Schrage B, Kalbacher D, Schwarzl M, Rübsamen N, Waldeyer C, Becher PM, Tigges E, Burkhoff D, Blankenberg S, Lubos E, Schäfer U, Westermann D.
J Am Heart Assoc. 2018: 15; 7(6):e007963. - Comparative analysis of balloon- versus mechanically-expandable transcatheter heart valves considering landing zone calcification.
Schofer N, Deuschl F, Schön G, Seiffert M, Linder M, Schaefer A, Schirmer J, Lubos E, Reichenspurner H, Blankenberg S, Conradi L, Schäfer U.
J Cardiol. 2018: 71(6):540-546. - Real-world experience using the ACURATE neo prosthesis: 30-day outcomes of 1,000 patients enrolled in the SAVI TF registry.
Möllmann H, Hengstenberg C, Hilker M, Kerber S, Schäfer U, Rudolph T, Linke A, Franz N, Kuntze T, Nef H, Kappert U, Walther T, Zembala MO, Toggweiler S, Kim WK.
EuroIntervention. 2018: 13(15):e1764-e1770. - Treatment of Aortic Stenosis With a Self-Expanding, Resheathable Transcatheter Valve: One-Year Results of the International Multicenter Portico Transcatheter Aortic Valve Implantation System Study.
Linke A, Holzhey D, Möllmann H, Manoharan G, Schäfer U, Frerker C, Worthley SG, van Boven AJ, Redwood S, Kovac J, Butter C, Søndergaard L, Lauten A, Schymik G, Walther T.
Circ Cardiovasc Interv. 2018: 11(2):e005206. - First-in-human implantation of a novel self-expanding supra-annular transcatheter heart valve for transcatheter aortic valve implantation inside a small degenerated aortic surgical bioprosthesis.
Schäfer U, Kalbacher D, Voigtländer L, Conradi L.
Catheter Cardiovasc Interv. 2018: 92(7):1453-1457. - Right Ventricular Index for Risk Stratification of Patients with Pulmonary Arterial Hypertension.
Sinning C, Harbaum L, Schrage B, Rübsamen N, Magnussen C, Waschki B, Kleemann WH, Baaske KM, Kögler M, Ojeda F, Fischer C, Benjamin N, Westermann D, Zengin E, Schäfer U, Egenlauf B, Klose HF, Blankenberg S, Grünig E.
Respiration. 2018; 96(3):249-258. - Acute hemodynamic changes after MitraClip implantation comparing patients with degenerative and functional mitral regurgitation.
Schmidt T, Schlüter M, Thielsen T, Alessandrini H, Schewel D, Kreidel F, Schmoeckel M, Schäfer U, Kuck KH, Frerker C.
Structural Heart 2017; 5: 188-194. - Self-Expanding Transcatheter Aortic Valve System for Symptomatic High-Risk Patients With Severe Aortic Stenosis.
Reichenspurner H, Schaefer A, Schäfer U, Tchétché D, Linke A, Spence MS, Søndergaard L, LeBreton H, Schymik G, Abdel-Wahab M, Leipsic J, Walters DL, Worthley S, Kasel M, Windecker S.
J Am Coll Cardiol. 2017: 70(25):3127-3136. - First-in-human implantation of a novel transfemoral selfexpanding transcatheter heart valve to treat pure aortic regurgitation.
Schäfer U, Schirmer J, Niklas S, Harmel E, Deuschl F, Conradi L.
EuroIntervention. 2017: 13(11):1296-1299. - Transcatheter Aortic Valve Replacement in Pure Native Aortic Valve Regurgitation.
Yoon SH, Schmidt T, Bleiziffer S, Schofer N, Fiorina C, Munoz-Garcia AJ, Yzeiraj E, Amat-Santos IJ, Tchetche D, Jung C, Fujita B, Mangieri A, Deutsch MA, Ubben T, Deuschl F, Kuwata S, De Biase C, Williams T, Dhoble A, Kim WK, Ferrari E, Barbanti M, Vollema EM, Miceli A, Giannini C, Attizzani GF, Kong WKF, Gutierrez-Ibanes E, Jimenez Diaz VA, Wijeysundera HC, Kaneko H, Chakravarty T, Makar M, Sievert H, Hengstenberg C, Prendergast BD, Vincent F, Abdel-Wahab M, Nombela-Franco L, Silaschi M, Tarantini G, Butter C, Ensminger SM, Hildick-Smith D, Petronio AS, Yin WH, De Marco F, Testa L, Van Mieghem NM, Whisenant BK, Kuck KH, Colombo A, Kar S, Moris C, Delgado V, Maisano F, Nietlispach F, Mack MJ, Schofer J, Schäfer U, Bax JJ, Frerker C, Latib A, Makkar RR.
J Am Coll Cardiol. 2017: 70(22):2752-2763. - Comparison of latest generation transfemoral self-expandable and balloon-expandable transcatheter heart valves.
Schaefer A, Linder M, Seiffert M, Schoen G, Deuschl F, Schofer N, Schneeberger Y, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L.
Interact Cardiovasc Thorac Surg. 2017: 25(6):905-911. - The International Multicenter TriValve Registry: Which Patients Are Undergoing Transcatheter Tricuspid Repair?
Taramasso M, Hahn RT, Alessandrini H, Latib A, Attinger-Toller A, Braun D, Brochet E, Connelly KA, Denti P, Deuschl F, Englmaier A, Fam N, Frerker C, Hausleiter J, Juliard JM, Kaple R, Kreidel F, Kuck KH, Kuwata S, Ancona M, Malasa M, Nazif T, Nickenig G, Nietlispach F, Pozzoli A, Schäfer U, Schofer J, Schueler R, Tang G, Vahanian A, Webb JG, Yzeiraj E, Maisano F, Leon MB.
JACC Cardiovasc Interv. 2017: 10(19):1982-1990. - Short-Term Outcome and Hemodynamic Performance of Next-Generation Self-Expanding Versus Balloon-Expandable Transcatheter Aortic Valves in Patients With Small Aortic Annulus: A Multicenter Propensity-Matched Comparison.
Mauri V, Kim WK, Abumayyaleh M, Walther T, Moellmann H, Schäfer U, Conradi L, Hengstenberg C, Hilker M, Wahlers T, Baldus S, Rudolph V, Madershahian N, Rudolph TK.
Circ Cardiovasc Interv. 2017: 10(10):e005013. - Transcatheter Mitral Valve Replacement for Degenerated Bioprosthetic Valves and Failed Annuloplasty Rings.
Yoon SH, Whisenant BK, Bleiziffer S, Delgado V, Schofer N, Eschenbach L, Fujita B, Sharma R, Ancona M, Yzeiraj E, Cannata S, Barker C, Davies JE, Frangieh AH, Deuschl F, Podlesnikar T, Asami M, Dhoble A, Chyou A, Masson JB, Wijeysundera HC, Blackman DJ, Rampat R, Taramasso M, Gutierrez-Ibanes E, Chakravarty T, Attizzani GF, Kaneko T, Wong SC, Sievert H, Nietlispach F, Hildick-Smith D, Nombela-Franco L, Conradi L, Hengstenberg C, Reardon MJ, Kasel AM, Redwood S, Colombo A, Kar S, Maisano F, Windecker S, Pilgrim T, Ensminger SM, Prendergast BD, Schofer J, Schäfer U, Bax JJ, Latib A, Makkar RR.
J Am Coll Cardiol. 2017: 70(9):1121-1131. - Compassionate use of the PASCAL transcatheter mitral valve repair system for patients with severe mitral regurgitation: a multicentre, prospective, observational, first-in-man study.
Praz F, Spargias K, Chrissoheris M, Büllesfeld L, Nickenig G, Deuschl F, Schueler R, Fam NP, Moss R, Makar M, Boone R, Edwards J, Moschovitis A, Kar S, Webb J, Schäfer U, Feldman T, Windecker S.
Lancet. 2017: 390(10096):773-780. - Implantation and 30-Day Follow-Up on All 4 Valve Sizes Within the Portico Transcatheter Aortic Bioprosthetic Family.
Möllmann H, Linke A, Holzhey DM, Walther T, Manoharan G, Schäfer U, Heinz-Kuck K, Van Boven AJ, Redwood SR, Kovac J, Butter C, Søndergaard L, Lauten A, Schymik G, Worthley SG.
JACC Cardiovasc Interv. 2017: 10(15):1538-1547. - Percutaneous Edge-to-Edge Repair of Recurrent Severe Mitral Regurgitation After Surgical Mitral Valve Repair.
Braun D, Frerker C, Körber MI, Gaemperli O, Patzelt J, Schäfer U, Hammerstingl C, Boekstegers P, Ott I, Ince H, Thiele H, Hausleiter J.
J Am Coll Cardiol. 2017: 70(4):504-505. - Safety and Efficacy of the Percutaneous Transaxillary Access for Transcatheter Aortic Valve Implantation using various Transcatheter Heart Valves in 100 Consecutive Patients
Schäfer U, Deuschl F, Schofer N, Frerker C, Schmidt T, Kuck KH, Kreidel F, Schirmer J, Mizote I, Reichenspurner H, Blankenberg S, Treede H, Conradi L.
Int J Cardiol. 2017: Int J Cardiol. 232:247-254. - Effect of valve design and anticoagulation strategy on 30-day clinical outcomes in transcatheter aortic valve replacement: Results from the BRAVO 3 randomized trial.
Linke A, Chandrasekhar J, Sartori S, Lefevre T, van Belle E, Schäfer U, Tchetche D, Sardella G, Webb J, Colombo A, Windecker S, Vogel B, Farhan S, Sorrentino S, Sharma M, Snyder C, Asgar A, Dumonteil N, Tamburino C, Hink U, Violini R, Stella P, Bernstein D, Deliargyris E, Hengstenberg C, Baber U, Mehran R, Anthopoulos P, Dangas G; BRAVO-3 Investigators.
Catheter Cardiovasc Interv. 2017: 90(6):1016-1026. - Structural Valve Deterioration of a Subcoronary Implanted Stentless Bioprosthesis: How to Treat?
Harmel EK, Conradi L, Schäfer U, Deuschl F, Schofer N, Blankenberg S, Reichenspurner H, Girdauskas E.
Ann Thorac Surg. 2017: 104(1):e53-e55. - First experience with transfemoral transcatheter aortic valve implantation without prior balloon pre-dilatation using a latest generation repositionable and retrievable transcatheter heart valve†.
Schaefer A, Harmel E, Seiffert M, Reichart D, Deuschl F, Schofer N, Schneeberger Y, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L.
Interact Cardiovasc Thorac Surg. 2017: 24(5):659-662. - Prognostic implication of post-MitraClip vena contracta area in heart failure patients with functional mitral regurgitation.
Alessandrini H, Kreidel F, Schlüter M, Frerker C, Schmidt T, Thielsen T, Schäfer U, Kuck KH.
EuroIntervention. 2017: 12(16):1946-1953. - Outcomes in Transcatheter Aortic Valve Replacement for Bicuspid Versus Tricuspid Aortic Valve Stenosis.
Yoon SH, Bleiziffer S, De Backer O, Delgado V, Arai T, Ziegelmueller J, Barbanti M, Sharma R, Perlman GY, Khalique OK, Holy EW, Saraf S, Deuschl F, Fujita B, Ruile P, Neumann FJ, Pache G, Takahashi M, Kaneko H, Schmidt T, Ohno Y, Schofer N, Kong WKF, Tay E, Sugiyama D, Kawamori H, Maeno Y, Abramowitz Y, Chakravarty T, Nakamura M, Kuwata S, Yong G, Kao HL, Lee M, Kim HS, Modine T, Wong SC, Bedgoni F, Testa L, Teiger E, Butter C, Ensminger SM, Schäfer U, Dvir D, Blanke P, Leipsic J, Nietlispach F, Abdel-Wahab M, Chevalier B, Tamburino C, Hildick-Smith D, Whisenant BK, Park SJ, Colombo A, Latib A, Kodali SK, Bax JJ, Søndergaard L, Webb JG, Lefèvre T, Leon MB, Makkar R.
J Am Coll Cardiol. 2017: 69(21):2579-2589. - Direct percutaneous transaxillary implantation of a novel self-expandable transcatheter heart valve for aortic stenosis.
Deuschl F, Schofer N, Seiffert M, Hakmi S, Mizote I, Schaefer A, Schirmer J, Reichenspurner H, Blankenberg S, Conradi L, Schäfer U.
Catheter Cardiovasc Interv. 2017: 90(7):1167-1174. - Impact of tricuspid valve regurgitation in surgical high-risk patients undergoing MitraClip implantation: results from the TRAMI registry.
Kalbacher D, Schäfer U, von Bardeleben RS, Zuern CS, Bekeredjian R, Ouarrak T, Sievert H, Nickenig G, Boekstegers P, Senges J, Schillinger W, Lubos E.
EuroIntervention. 2017: 12(15):e1809-e1816. - Percutaneous coronary intervention for ostial and bifurcation lesions using the Szabo technique: a single center experience.
Schrage B, Schwarzl M, Waldeyer C, Becher PM, Sinning C, Schäfer U, Seiffert M, Zengin-Sahm E, Blankenberg S, Westermann D.
Minerva Cardioangiol. 2017: 65(4):331-335. - Impact of interaction of diabetes mellitus and impaired renal function on prognosis and the incidence of acute kidney injury in patients undergoing transcatheter aortic valve replacement (TAVR).
Schewel D, Zavareh M, Schewel J, Thielsen T, Schmidt T, Schäfer U, Kuck KH, Frerker C.
Int J Cardiol. 2017: 232:147-154. - Transcatheter Tricuspid Valve-In-Ring and Aortic Valve-In-Valve Implantation.
Reichart D, Schofer N, Deuschl F, Schaefer A, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L.
Thorac Cardiovasc Surg Rep. 2017: 6(1):e29-e31. - Transcatheter implantation of aortic valve prostheses into degenerated mitral valve bioprostheses and failed annuloplasty rings: outcomes according to access route and Mitral Valve Academic Research Consortium (MVARC) criteria.
Frerker C, Schmidt T, Schlüter M, Bader R, Schewel J, Schewel D, Thielsen T, Kreidel F, Alessandrini H, Schlingloff F, Schäfer U, Kuck KH.
EuroIntervention. 2016: 12(12):1520-1526. - Histological Findings and Predictors of Cerebral Debris From Transcatheter Aortic Valve Replacement: The ALSTER Experience.
Schmidt T, Akdag O, Wohlmuth P, Thielsen T, Schewel D, Schewel J, Alessandrini H, Kreidel F, Bader R, Romero M, Ladich E, Virmani R, Schäfer U, Kuck KH, Frerker C.
J Am Heart Assoc. 2016. 5(11):e004399 - Redo TAVI: initial experience at two German centres.
Schmidt T, Frerker C, Alessandrini H, Schlüter M, Kreidel F, Schäfer U, Thielsen T, Kuck KH, Jose J, Holy EW, El-Mawardy M, Allali A, Richardt G, Abdel-Wahab M.
EuroIntervention. 2016: 12(7):875-82. - Transcatheter valve-in-valve implantation versus redo surgical aortic valve replacement in patients with failed aortic bioprostheses.
Silaschi M, Wendler O, Seiffert M, Castro L, Lubos E, Schirmer J, Blankenberg S, Reichenspurner H, Schäfer U, Treede H, MacCarthy P, Conradi L.
Interact Cardiovasc Thorac Surg. 2017: 24(1):63-70. - Transcatheter Aortic Valve Replacement With Early- and New-Generation Devices in Bicuspid Aortic Valve Stenosis.
Yoon SH, Lefèvre T, Ahn JM, Perlman GY, Dvir D, Latib A, Barbanti M, Deuschl F, De Backer O, Blanke P, Modine T, Pache G, Neumann FJ, Ruile P, Arai T, Ohno Y, Kaneko H, Tay E, Schofer N, Holy EW, Luk NHV, Yong G, Lu Q, Kong WKF, Hon J, Kao HL, Lee M, Yin WH, Park DW, Kang SJ, Lee SW, Kim YH, Lee CW, Park SW, Kim HS, Butter C, Khalique OK, Schäfer U, Nietlispach F, Kodali SK, Leon MB, Ye J, Chevalier B, Leipsic J, Delgado V, Bax JJ, Tamburino C, Colombo A, Søndergaard L, Webb JG, Park SJ.
J Am Coll Cardiol. 2016: 68(11):1195-1205. - Impact of Preprocedural Left Ventricular Ejection Fraction on 1-Year Outcomes After MitraClip Implantation (from the ACCESS-EU Phase I, a Prospective, Multicenter, Nonrandomized Postapproval Study of the MitraClip Therapy in Europe).
Schäfer U, Maisano F, Butter C, Franzen O, Baldus S, Hausleiter J, Ussia GP, Sievert H, Geist V, Widder JD, Moccetti T, Schillinger W.
Am J Cardiol. 2016: 118(6):873-880. - A case of successful Mitraclip implantation in a patient having a large coaptation gap under extracorporeal membrane oxygenation (ECMO).
Mizote I, Schirmer J, Schäfer U.
Catheter Cardiovasc Interv. 2018: 91(4):827-830. - Interventional Treatment of a Failing Pulmonic and Tricuspid Bioprosthesis in Hedinger Syndrome.
Zengin E, Sinning C, Schäfer U.
JACC Cardiovasc Interv. 2016: 9(15):e145-6. - Transcatheter Aortic Valve Replacement Using the Portico System: 10 Things to Remember.
Tzikas A, Amrane H, Bedogni F, Brambilla N, Kefer J, Manoharan G, Makkar R, Möllman H, Rodés-Cabau J, Schäfer U, Settergren M, Spargias K, van Boven A, Walther T, Worthley SG, Sondergaard L.
J Interv Cardiol. 2016: 29(5):523-529. - First-in-man treatment of a degenerated mitral surgical valve with the mechanical expanding Lotus™ valve.
Schäfer U, Conradi L, Lubos E, Deuschl F, Schofer N, Treede H, Schirmer J, Vogel B, Reichenspurner H, Blankenberg S.
EuroIntervention. 2016: 12(4):515-8. - Gender in the ACCESS-EU registry: a prospective, multicentre, non-randomised post-market approval study of MitraClip® therapy in Europe.
Gafoor S, Sievert H, Maisano F, Baldus S, Schäfer U, Hausleiter J, Butter C, Ussia GP, Geist V, Widder JD, Moccetti T, Schillinger W, Franzen O.
EuroIntervention. 2016: 12(2):e257-64. - Radiation exposure during the implantation of bioabsorbable vascular scaffolds versus drug-eluting stents in non-complex coronary lesions: a matched-cohort study.
Schrage B, Seiffert M, Müllerleile K, Zengin E, Lubos E, Sinning C, Schäfer U, Sydow K, Blankenberg S, Westermann D.
Minerva Cardioangiol. 2017: 65(1):1-7. - Histology of debris captured by a cerebral protection system during transcatheter valve-in-valve implantation.
Schmidt T, Schlüter M, Alessandrini H, Akdag O, Schewel D, Schewel J, Thielsen T, Kreidel F, Bader R, Romero M, Ladich E, Virmani R, Schäfer U, Kuck KH, Frerker C.
Heart. 2016: 02(19):1573-80. - A case of anomalous left coronary artery obstruction caused by lotus valve implantation.
Mizote I, Conradi L, Schäfer U.
Catheter Cardiovasc Interv. 2017: 90(7):1227-1231. - Baseline anemia and its impact on midterm outcome after transcatheter aortic valve implantation.
Seiffert M, Conradi L, Gutwein A, Schön G, Deuschl F, Schofer N, Becker N, Schirmer J, Reichenspurner H, Blankenberg S, Treede H, Schäfer U.
Catheter Cardiovasc Interv. 2017: 89(1):E44-E52. - Emergency transcatheter aortic valve replacement in patients with cardiogenic shock due to acutely decompensated aortic stenosis.
Frerker C, Schewel J, Schlüter M, Schewel D, Ramadan H, Schmidt T, Thielsen T, Kreidel F, Schlingloff F, Bader R, Wohlmuth P, Schäfer U, Kuck KH.
EuroIntervention. 2016: 1(13):1530-6. - Combined rendezvous approach with the Direct Flow Medical® aortic valve prosthesis to treat aortic and mitral stenosis.
Sinning C, Conradi L, Deuschl FG, Schofer N, Hakmi S, Schäfer U.
Int J Cardiol. 2016: 214:284-5. - Improving outcomes: case-matched comparison of novel second-generation versus first-generation self-expandable transcatheter heart valves.
Schaefer A, Treede H, Schoen G, Deuschl F, Schofer N, Schneeberger Y, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L.
Eur J Cardiothorac Surg. 2016: 50(2):368-73. - Repeat transcatheter aortic valve implantation using a latest generation balloon-expandable device for treatment of failing transcatheter heart valves.
Schaefer A, Treede H, Seiffert M, Deuschl F, Schofer N, Schneeberger Y, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L.
J Cardiothorac Surg. 2016 Jan 15;11:2. doi: 10.1186/s13019-016-0398-y. - Transcatheter Mitral Valve Repair in Surgical High-Risk Patients: Gender-Specific Acute and Long-Term Outcomes.
Tigges E, Kalbacher D, Thomas C, Appelbaum S, Deuschl F, Schofer N, Schlüter M, Conradi L, Schirmer J, Treede H, Reichenspurner H, Blankenberg S, Schäfer U, Lubos E.
Biomed Res Int. 2016; 2016:3934842. doi: 10.1155/2016/3934842. Epub 2016 Mar 2. - Applicability of next generation balloon-expandable transcatheter heart valves in aortic annuli exceeding formally approved dimensions.
Schaefer A, Linder M, Treede H, Deuschl F, Schofer N, Seiffert M, Schneeberger Y, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L.
Clin Res Cardiol. 2016 Jul; 105(7):585-91. - Targeting systolic anterior motion and left ventricular outflow tract obstruction in hypertrophic obstructed cardiomyopathy with a MitraClip.
Schäfer U, Frerker C, Thielsen T, Schewel D, Bader R, Kuck KH, Kreidel F.
EuroIntervention. 2015. 11(8):942-7. - Thirty-day VARC-2 and performance data of a new self-expanding transcatheter aortic heart valve.
Treede H, Lubos E, Conradi L, Deuschl F, Asch FM, Weissman NJ, Schofer N, Schirmer J, Koschyk D, Blankenberg S, Reichenspurner H, Schäfer U.
EuroIntervention. 2015: 11(7):785-92. - Bivalirudin Versus Heparin Anticoagulation in Transcatheter Aortic Valve Replacement: The Randomized BRAVO-3 Trial.
Dangas GD, Lefèvre T, Kupatt C, Tchetche D, Schäfer U, Dumonteil N, Webb JG, Colombo A, Windecker S, Ten Berg JM, Hildick-Smith D, Mehran R, Boekstegers P, Linke A, Tron C, Van Belle E, Asgar AW, Fach A, Jeger R, Sardella G, Hink HU, Husser O, Grube E, Deliargyris EN, Lechthaler I, Bernstein D, Wijngaard P, Anthopoulos P, Hengstenberg C; BRAVO-3 Investigators.
J Am Coll Cardiol. 2015 Dec 29; 66(25):2860-2868. - Trends in Surgical Aortic Valve Replacement in More Than 3,000 Consecutive Cases in the Era of Transcatheter Aortic Valve Implantations.
Silaschi M, Conradi L, Treede H, Reiter B, Schäfer U, Blankenberg S, Reichenspurner H.
Thorac Cardiovasc Surg. 2016: 64(5):382-9. - Percutaneous ventricular restoration (PVR) therapy using the Parachute device in 100 subjects with ischaemic dilated heart failure: one-year primary endpoint results of PARACHUTE III, a European trial.
Thomas M, Nienaber CA, Ince H, Erglis A, Vukcevic V, Schäfer U, Ferreira RC, Hardt S, Verheye S, Gama Ribeiro V, Sugeng L, Tamburino C.
EuroIntervention. 2015: 11(6):710-7. - Transseptal and transmitral Parachute® implantation in conjunction with "MitraClipping".
Schäfer U, Lubos E, Deuschl F, Schofer N, Grahn H, Conradi L, Schirmer J, Reichenspurner H, Schmidt T, Frerker C, Kuck KH, Westermann D, Blankenberg S, Treede H.
EuroIntervention. 2015: 11(6):673-81. - First in human implantation of the mechanical expanding Lotus® valve in degenerated surgical valves in mitral position.
Schäfer U, Conradi L, Lubos E, Deuschl F, Schofer N, Seiffert M, Treede H, Schirmer J, Reichenspurner H, Blankenberg S.
Catheter Cardiovasc Interv. 2015: 86(7):1280-6. - Repeat MitraClip Therapy for Significant Recurrent Mitral Regurgitation in High Surgical Risk Patients: Impact of Loss of Leaflet Insertion.
Kreidel F, Frerker C, Schlüter M, Alessandrini H, Thielsen T, Geidel S, Schäfer U, Kuck KH.
JACC Cardiovasc Interv. 2015: 8(11):1480-9. - Transcatheter valve-in-valve therapy using 6 different devices in 4 anatomic positions: Clinical outcomes and technical considerations.
Conradi L, Silaschi M, Seiffert M, Lubos E, Blankenberg S, Reichenspurner H, Schäfer U, Treede H.
J Thorac Cardiovasc Surg. 2015: 150(6):1557-65, 1567.e1-3. - Reply: von Willebrand Disease After TAVR: The Missing Link?
Spangenberg T, Budde U, Schewel D, Frerker C, Thielsen T, Kuck KH, Schäfer U.
JACC Cardiovasc Interv. 2015: 8(9):1266-1267. - Reducing radiation exposure during invasive coronary angiography and percutaneous coronary interventions implementing a simple four-step protocol.
Seiffert M, Ojeda F, Müllerleile K, Zengin E, Sinning C, Waldeyer C, Lubos E, Schäfer U, Sydow K, Blankenberg S, Westermann D.
Clin Res Cardiol. 2015: (6):500-506. - Valve-in-Valve Procedures in Failing Biological Xenografts Using a Novel Balloon-Expandable Device: Experience in Aortic, Mitral, and Tricuspid Positions.
Schaefer A, Conradi L, Seiffert M, Lubos E, Blankenberg S, Reichenspurner H, Schäfer U, Treede H.
J Thorac Cardiovasc Surg. 2016: 64(5):366-73. - Invasive hemodynamic assessments during transcatheter aortic valve implantation: comparison of patient outcomes in higher vs. lower transvalvular gradients with respect to left ventricular ejection fraction.
Schewel J, Schewel D, Frerker C, Wohlmuth P, Kuck KH, Schäfer U.
Clin Res Cardiol. 2016: 105(1):59-71. - Device landing zone calcification and its impact on residual regurgitation after transcatheter aortic valve implantation with different devices.
Seiffert M, Fujita B, Avanesov M, Lunau C, Schön G, Conradi L, Prashovikj E, Scholtz S, Börgermann J, Scholtz W, Schäfer U, Lund G, Ensminger S, Treede H.
Eur Heart J Cardiovasc Imaging. 2016: 17(5):576-84. - Treatment of acquired von Willebrand syndrome in aortic stenosis with transcatheter aortic valve replacement.
Spangenberg T, Budde U, Schewel D, Frerker C, Thielsen T, Kuck KH, Schäfer U.
JACC Cardiovasc Interv. 2015: 8(5):692-700. - Transfemoral TAVI without pre-dilatation using balloon-expandable devices: a case-matched analysis.
Conradi L, Schaefer A, Seiffert M, Schirmer J, Schäfer U, Schön G, Blankenberg S, Reichenspurner H, Treede H, Diemert P.
Clin Res Cardiol. 2015 Sep; 104(9):735-42. - How should I treat a severely symptomatic, high-risk female patient with degenerated mitral (Carpentier-Edwards porcine) and aortic (Sorin Mitroflow) bioprostheses?
Berti S, Cerillo AG, Murzi M, Mariani M, Marchi F, Schäfer U, Attia R, Bapat V, Himbert D, Brochet E, Depoix JP, Nataf P, Vahanian A.
EuroIntervention. 2015: 10(10):1250-2. - Percutaneous left atrial appendage closure in patients with left atrial appendage thrombus.
Meincke F, Kreidel F, von Wedel J, Schäfer U, Kuck KH, Bergmann MW.
EuroIntervention. 2015: 10(10):1208. - Reducing radiation exposure during invasive coronary angiography and percutaneous coronary interventions implementing a simple four-step protocol.
Seiffert M, Ojeda F, Müllerleile K, Zengin E, Sinning C, Waldeyer C, Lubos E, Schäfer U, Sydow K, Blankenberg S, Westermann D.
Clin Res Cardiol. 2015: 104(6):500-6. - Simultaneous Double Clipping Delivery Guide Strategy in Complex Mitral Regurgitation.
Schäfer U, Frerker C, Kreidel F, Kuck KH.
J Heart Valve Dis. 2015: 24(1):57-65. - Comparison of outcomes of patients with left ventricular ejection fractions ≤30% versus ≥30% having transcatheter aortic valve implantation (from the German Transcatheter Aortic Valve Interventions Registry).
Schäfer U, Zahn R, Abdel-Wahab M, Gerckens U, Linke A, Schneider S, Eggebrecht H, Sievert H, Figulla HR, Senges J, Kuck KH; German TAVI Registry.
Am J Cardiol. 2015: 115(5):656-63. - Impact of transcatheter aortic valve implantation (TAVI) on pulmonary hyper-tension and clinical outcome in patients with severe aortic valvular stenosis.
Schewel D, Schewel J, Martin J, Voigtländer L, Frerker C, Wohlmuth P, Thielsen T, Kuck KH, Schäfer U.
Clin Res Cardiol. 2015: 104(2):164-74. - Impact of kidney function on mortality after transcatheter valve implantation in patients with severe aortic valvular stenosis.
Voigtländer L, Schewel J, Martin J, Schewel D, Frerker C, Wohlmuth P, Thielsen T, Kuck KH, Schäfer U.
Int J Cardiol. 2015: 178:275-81. - Blood transfusion is associated with impaired outcome after transcatheter aortic valve implantation.
Seiffert M, Conradi L, Terstesse AC, Koschyk D, Schirmer J, Schnabel RB, Wilde S, Ojeda FM, Reichenspurner H, Blankenberg S, Schäfer U, Treede H, Diemert P.
Catheter Cardiovasc Interv. 2015: 85(3):460-7. - New evidence for favourable effects on haemodynamics and ventricular performance after Parachute-implantation in humans.
Schmidt T, Frerker C, Thielsen T, Dotz I, Wohlmuth P, Kuck KH, Schäfer U.
Eur J Heart Fail. 2014: 16(10):1112-9. - Simultaneous double clipping delivery guide strategy for treatment of severe coaptation failure in functional mitral regurgitation.
Schäfer U, Frerker C, Kreidel F.
Heart Lung Circ. 2015 Jan; 24(1):98-102. - Initial German experience with transapical implantation of a second-generation transcatheter heart valve for the treatment of aortic regurgitation.
Seiffert M, Bader R, Kappert U, Rastan A, Krapf S, Bleiziffer S, Hofmann S, Arnold M, Kallenbach K, Conradi L, Schlingloff F, Wilbring M, Schäfer U, Diemert P, Treede H.
JACC Cardiovasc Interv. 2014: 7(10):1168-74. - Transcatheter aortic valve implantation in failed bioprosthetic surgical valves.
Dvir D, Webb JG, Bleiziffer S, Pasic M, Waksman R, Kodali S, Barbanti M, Latib A, Schäfer U, Rodés-Cabau J, Treede H, Piazza N, Hildick-Smith D, Himbert D, Walther T, Hengstenberg C, Nissen H, Bekeredjian R, Presbitero P, Ferrari E, Segev A, de Weger A, Windecker S, Moat NE, Napodano M, Wilbring M, Cerillo AG, Brecker S, Tchetche D, Lefèvre T, De Marco F, Fiorina C, Petronio AS, Teles RC, Testa L, Laborde JC, Leon MB, Kornowski R; Valve-in-Valve International Data Registry Investigators.
JAMA. 2014: 312(2):162-70. - Predictors of 1-year mortality in patients with aortic regurgitation after transcatheter aortic valve implantation: an analysis from the multicentre German TAVI registry.
Abdel-Wahab M, Zahn R, Gerckens U, Linke A, Sievert H, Schäfer U, Kahlert P, Hambrecht R, Sack S, Hoffmann E, Senges J, Schneider S, Richardt G; German TAVI Registry Investigators.
Heart. 2014: 100(16):1250-6. - Transcatheter aortic valve implantation of a second-generation valve for pure aortic regurgitation: procedural outcome, haemodynamic data and follow-up.
Schlingloff F, Schäfer U, Frerker C, Schmoeckel M, Bader R.
Interact Cardiovasc Thorac Surg. 2014: 19(3):388-93. - Balloon-expandable valves for degenerated mitral xenografts or failing surgical rings.
Schäfer U, Bader R, Frerker C, Schewel D, Thielsen T, Schmoeckel M, Kreidel F, Kuck KH.
EuroIntervention. 2014: 10(2):260-8. - Valve-in-valve implantation of a novel and small self-expandable transcatheter heart valve in degenerated small surgical bioprostheses: the Hamburg experience.
Diemert P, Seiffert M, Frerker C, Thielsen T, Kreidel F, Bader R, Schirmer J, Conradi L, Koschyk D, Schnabel R, Reichenspurner H, Blankenberg S, Kuck KH, Treede H, Schäfer U.
Catheter Cardiovasc Interv. 2014: 84(3):486-93. - Comparison of balloon-expandable vs self-expandable valves in patients undergoing transcatheter aortic valve replacement: the CHOICE randomized clinical trial.
Abdel-Wahab M, Mehilli J, Frerker C, Neumann FJ, Kurz T, Tölg R, Zachow D, Guerra E, Massberg S, Schäfer U, El-Mawardy M, Richardt G; CHOICE investigators.
JAMA. 2014: 16; 311(15):1503-14. - Treatment of aortic stenosis with a self-expanding transcatheter valve: the International Multi-centre ADVANCE Study.
Linke A, Wenaweser P, Gerckens U, Tamburino C, Bosmans J, Bleiziffer S, Blackman D, Schäfer U, Müller R, Sievert H, Søndergaard L, Klugmann S, Hoffmann R, Tchétché D, Colombo A, Legrand VM, Bedogni F, lePrince P, Schuler G, Mazzitelli D, Eftychiou C, Frerker C, Boekstegers P, Windecker S, Mohr FW, Woitek F, Lange R, Bauernschmitt R, Brecker S; ADVANCE study Investigators.
Eur Heart J. 2014: 35(38):2672-84. - Percutaneous interventional mitral regurgitation treatment using the Mitra-Clip system.
Boekstegers P, Hausleiter J, Baldus S, von Bardeleben RS, Beucher H, Butter C, Franzen O, Hoffmann R, Ince H, Kuck KH, Rudolph V, Schäfer U, Schillinger W, Wunderlich N.
Clin Res Cardiol. 2014: 103(2): 85–96. - Hybrid approach for redo mitral valve surgery with safe intermittent catheter balloon occlusion of a patent arterial T-graft.
Geidel S, Schäfer U, Hassan K, Oberhoffer M, Bader R, Kuck KH, Schmoeckel M.
Herz. 2013: 38(7): 736– 737. - Interventionelle Rekonstruktion der Mitralklappe mit dem Mitraclip-Verfahren. Mitraclip Leitlinie.
Boekstegers P, Hausleiter J, Baldus S, Bardeleben RS, Beucher H, Butter C, Franzen O, Hoffmann R, Ince H, Kuck KH, Rudolph V, Schäfer U, Schillinger W, Wunderlich N.
Clin Res Cardiol 2013: Volume 7, Issue 2: 91–104. - MitraClip implantation as a new treatment strategy against systolic anterior motion-induced outflow tract obstruction in hypertrophic obstructive cardiomyopathy.
Schäfer U, Kreidel F, Frerker C.
Heart Lung Circ. 2014: 23(5):e131-5. - Clinical impact of paravalvular leaks on biomarkers and survival after transcatheter aortic valve implantation.
Schewel D, Frerker C, Schewel J, Wohlmuth P, Meincke F, Thielsen T, Kreidel F, Kuck KH, Schäfer U.
Catheter Cardiovasc Interv. 2015: 85(3):502-14. - MitraClip® via direct right atrial access in case of a missing inferior vena cava.
Frerker C, Meincke F, Seibert HP, Alessandrini H, Kreidel F, Caspary M, Busse C, Schäfer U, Kuck KH.
EuroIntervention. 2013: 9(5):643-7. - Transcatheter access route options for treatment of degenerated mitral valve prosthesis with a balloon-expandable biological valve.
Schäfer U, Frerker C, Bader R, Schmoeckel M, Busse C, Kuck KH.
Catheter Cardiovasc Interv. 2013: 82(6):999-1003. - Clinical outcomes through 12 months in patients with degenerative mitral regurgitation treated with the MitraClip® device in the ACCESS-EUrope Phase I trial.
Reichenspurner H, Schillinger W, Baldus S, Hausleiter J, Butter C, Schäefer U, Pedrazzini G, Maisano F; ACCESS-EU Phase I Investigators.
Eur J Cardiothorac Surg. 2013: 44(4):e280-8. - Transapical aortic valve (JenaValve) implantation for severe aortic insufficiency and aortic aneurysm.
Schlingloff F, Frerker C, Schäfer U, Bader R.
J Thorac Cardiovasc Surg. 2013: 146(4):e40-1. - Percutaneous mitral valve interventions in the real world: early and 1-year results from the ACCESS-EU, a prospective, multicenter, nonrandomized post-approval study of the MitraClip therapy in Europe.
Maisano F, Franzen O, Baldus S, Schäfer U, Hausleiter J, Butter C, Ussia GP, Sievert H, Richardt G, Widder JD, Moccetti T, Schillinger W.
J Am Coll Cardiol. 2013: 62(12):1052-1061. - Aortic aneurysm 18 month after transfemoral implantation of a self-expandable aortic valve prosthesis.
Schäfer U, Frerker C, Kuck KH.
Catheter Cardiovasc Interv. 2013: 82(2):321-3. - Transcatheter aortic valve replacement with a new self-expanding transcatheter heart valve and motorized delivery system.
Binder RK, Schäfer U, Kuck KH, Wood DA, Moss R, Leipsic J, Toggweiler S, Freeman M, Ostry AJ, Frerker C, Willson AB, Webb JG.
JACC Cardiovasc Interv. 2013 Mar; 6(3):301-7. - Transcatheter aortic valve implantation for pure severe native aortic valve regurgitation.
Roy DA, Schäfer U, Guetta V, Hildick-Smith D, Möllmann H, Dumonteil N, Modine T, Bosmans J, Petronio AS, Moat N, Linke A, Moris C, Champagnac D, Parma R, Ochala A, Medvedofsky D, Patterson T, Woitek F, Jahangiri M, Laborde JC, Brecker SJ.
J Am Coll Cardiol. 2013: 61(15):1577-84. - Complete crush of a balloon-expandable bioprosthesis after prolonged cardiopulmonary resuscitation.
Spangenberg T, Frerker C, Bader R, Schäfer U.
Circ Cardiovasc Interv. 2013: 6(1):e1-2. - Imaging in mitral valve interventions.
Kreidel F, Alessandrini H, Frerker C, Thielsen T, Schäfer U, Kuck K.
Herz. 2013: 38(5): 474–483. - Transfemoral and transseptal valve-in-valve implantation into a failing mitral xenograft with a balloon-expandable biological valve
Schäfer U, Frerker C, Schewel D, Thielsen T, Meincke F, Kreidel F, Kuck KH.
Ann Thorac Surg. 2012: 94(6):2115-8. - Ipsilateral arterial access for management of vascular complication in transcatheter aortic valve implantation.
Frerker C, Schewel D, Kuck KH, Schäfer U.
Catheter Cardiovasc Interv. 2013: 81(4):592-602. - Transcatheter aortic valve implantation in patients with and without concomitant coronary artery disease: comparison of characteristics and early outcome in the German multicenter TAVI registry.
Abdel-Wahab M, Zahn R, Horack M, Gerckens U, Schuler G, Sievert H, Naber C, Voehringer M, Schäfer U, Senges J, Richardt G.
Clin Res Cardiol. 2012: 101(12):973-81. - Transjugular and transseptal treatment of a degenerated mitral valve prosthesis with a balloon-expandable biological valve.
Schäfer U, Frerker C, Busse C, Kuck KH.
Heart Lung Circ. 2012: 21(12):836-40. - Direct percutaneous access technique for transaxillary transcatheter aortic valve implantation: "the Hamburg Sankt Georg approach".
Schäfer U, Ho Y, Frerker C, Schewel D, Sanchez-Quintana D, Schofer J, Bijuklic K, Meincke F, Thielsen T, Kreidel F, Kuck KH.
JACC Cardiovasc Interv. 2012: 5(5):477-486. - Successful reposition and treatment of severe aortic paraprosthetic regurgitation after percutaneous implantation of a self-expandable biological valve.
Frerker C, Bergmann M, Schewel D, Busse C, Jensen F, Schmoeckel M, Schneider C, Kuck KH, Schäfer U.
J Cardiovasc Med (Hagerstown). 2012 May; 13(5):346-50. - Valve-in-valve transcatheter aortic valve implantation for degenerated bioprosthetic heart valves.
Eggebrecht H, Schäfer U, Treede H, Boekstegers P, Babin-Ebell J, Ferrari M, Möllmann H, Baumgartner H, Carrel T, Kahlert P, Lange P, Walther T, Erbel R, Mehta RH, Thielmann M.
JACC Cardiovasc Interv. 2011: 4(11):1218-27. - Mitral valve regurgitation in advanced heart failure: interventional or surgical treatment? For interventional treatment.
Frerker C, Schäfer U, Kuck KH.
Dtsch Med Wochenschr 2010: 135: 1–2. - U73122, an aminosteroid phospholipase C inhibitor, is a potent inhibitor of cardiac phospholipase D by a PIP2-dependent mechanism.
Burgdorf C, Schäfer U, Richardt G, Kurz T.
J Cardiovasc Pharmacol. 2010: 55(6):555-9. - Percutaneous approaches for mitral valve interventions--a real alternative technique for standard cardiac surgery?
Frerker C, Schäfer U, Schewel D, Krüger M, Malisius R, Schneider C, Geidel S, Bergmann M, Kuck KH.
Herz. 2009: 34(6):444-50. - The 1527 Ala=>Gly Polymorphism in the ATP-Binding Cassette Transporter ABCA7 is associated with Dyslipidemia and Metabolic Syndrome in Women – Results from the MONICA/KORA Echocardiographic Substudy.
Linsel-Nitschke P, Götz A, Schäfer U, Lieb W, Bruse P, Doering A, Loewel H, Mayer B, Schunkert H, Erdmann J.
Coronary Artery Disease 2007: HX07C0138: 149–152. - PAI-1-induction in experimental septic cardiomyopathy is associated with reduced norepinephrine overflow from the heart. Modulation of Sympathetic Activity by Tissue-Plasminogen Activator is Independent of Plasminogen and Urokinase.
Schäfer U, Linsel-Nitschke P, Hecht von Saldern D, Stölting I, Levi R, Schunkert H, Kurz T.
Coronary Artery Disease 2007: HX07C0144: 105–108. - Nitrosative stress and myocardial sarcoplasmic endoreticular calcium adenosine triphosphatase subtype 2a activity after lung resection in swine.
Heerdt PM, Lane P, Pan BY, Schäfer U, Crabtree M, Hong R, Singer AA, Levi R, Park BJ.
Anesthesiology. 2007: 107(6):954-62. - Targeted deletion of ectonucleoside triphosphate diphosphohydrolase 1/CD39 leads to desensitization of pre- and postsynaptic purinergic P2 receptors.
Schäfer U, Machida T, Broekman MJ, Marcus AJ, Levi R.
J Pharmacol Exp Ther. 2007: 322(3):1269-77. - Intracoronary enalaprilat during primary angioplasty: alleviation of post-ischemic neurohumoral and inflammatory stress?
Schäfer U, Kurz T, Bonnemeier H, Hartmann F, Schunkert H, Richardt G.
J Intern Med 2007: 261(2): 188–200. - Effects of intracoronary low-dose enalaprilat on ventricular repolarization dynamics after direct percutaneous intervention for acute myocardial infarction.
Bonnemeier H, Schäfer U, Kurz T, Ortak J, Hartmann F, Katus HA, Richardt G, Schunkert H.
Pacing Clin Electrophysiol. 2007: 30(5):631-7. - Modulation of sympathetic activity by tissue plasminogen activator is independent of plasminogen and urokinase.
Schäfer U, Vorlova S, Machida T, Melchor JP, Strickland S, Levi R.
J Pharmacol Exp Ther. 2007: 322(1):265-73 - Histamine H3-receptor signaling in cardiac sympathetic nerves: Identification of a novel MAPK-PLA2-COX-PGE2-EP3R pathway.
Levi R, Seyedi N, Schäfer U, Estephan R, Mackins CJ, Tyler E, Silver RB.
Biochem Pharmacol. 2007: 73(8):1146-56. - Low doses of intracoronary enalaprilat suppress reperfusion-associated ventricular arrhythmias after primary percutaneous coronary interventions for acute myocardial infarction.
Bonnemeier H, Schäfer U, Ortak J, Kurz T, Katus HA, Richardt G, Schunkert H.
Pacing Clin Electrophysiol. 2007: 30 Suppl 1:S160-5. - "The artichoke heart": the inverse counterpart of left ventricular apical ballooning.
Bonnemeier H, Ortak J, Burgdorf C, Bode F, Schäfer U, Hartmann F, Schunkert H.
Resuscitation. 2007: 72(3):342-3. - The plasminogen activator system modulates sympathetic nerve function.
Schäfer U, Machida T, Vorlova S, Strickland S, Levi R.
J Exp Med. 2006: 203(9):2191-200. - Cardiac mast cell-derived renin promotes local angiotensin formation, norepinephrine release, and arrhythmias in ischemia/reperfusion.
Mackins CJ, Kano S, Seyedi N, Schäfer U, Reid AC, Machida T, Silver RB, Levi R.
J Clin Invest. 2006: 116(4):1063-70. - Apical ballooning without apical ballooning.
Bonnemeier H, Schäfer U, Schunkert H.
Eur Heart J. 2006: 27(18):2246. - Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol.
Cacheaux LP, Topf N, Tibbs GR, Schäfer U, Levi R, Harrison NL, Abbott GW, Goldstein PA.
J Pharmacol Exp Ther. 2005: 315(2):517-25. - Ectonucleoside triphosphate diphosphohydrolase 1/CD39, localized in neurons of human and porcine heart, modulates ATP-induced norepinephrine exocytosis.
Machida T, Heerdt PM, Reid AC, Schäfer U, Silver RB, Broekman MJ, Marcus AJ, Levi R.
J Pharmacol Exp Ther. 2005: 313(2):570-7. - Mast cells: a unique source of renin.
Silver RB, Reid AC, Mackins CJ, Askwith T, Schäfer U, Herzlinger D, Levi R.
Proc Natl Acad Sci U S A. 2004: 101(37):13607-12. - Norepinephrine release is reduced by I(1)-receptors in addition to alpha(2)-adrenoceptors.
Raasch W, Jungbluth B, Schäfer U, Häuser W, Dominiak P.
Ann N Y Acad Sci. 2003; 1009:270-3. - Moxonidine displays a presynaptic alpha-2-adrenoceptor-dependent synergistic sympathoinhibitory action at imidazoline-1 receptors.
Schäfer U, Burgdorf C, Engelhardt A, Raasch W, Kurz T, Richardt G.
Ann N Y Acad Sci. 2003: 1009:265-9. - Modification of noradrenaline release in pithed spontaneously hypertensive rats by I1-binding sites in addition to alpha2-adrenoceptors.
Raasch W, Jungbluth B, Schäfer U, Häuser W, Dominiak P.
J Pharmacol Exp Ther. 2003: 304(3):1063-71. - Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors.
Schäfer U, Burgdorf C, Engelhardt A, Kurz T, Richardt G.
J Pharmacol Exp Ther. 2002: 303(3):1163-70. - Effect of ACE-inhibitor ramiprilat and AT1-receptor antagonist candesartan on cardiac norepinephrine release: comparison between ischemic and nonischemic conditions.
Richardt D, Wolfrum S, Büttner C, Schäfer U, Dendorfer A, Kurz T, Richardt G.
J Cardiovasc Pharmacol. 2002: 40(4):641-6. - Impaired coronary flow and left ventricular dysfunction after mechanical recanalization in acute myocardial infarction: role of neurohumoral activation?
Schäfer U, Kurz T, Jain D, Hartmann F, Dendorfer A, Tölg R, Raasch W, Dominiak P, Katus H, Richardt G.
Basic Res Cardiol. 2002: 97(5):399-408. - Drug-induced lupus erythematosus by amiodarone.
Sheikhzadeh A, Schäfer U, Schnabel A.
Arch Intern Med. 2002: 162(7):834-6. - Agmatine, an endogenous ligand at imidazoline binding sites, does not antagonize the clonidine-mediated blood pressure reaction.
Raasch W, Schäfer U, Qadri F, Dominiak P.
Br J Pharmacol. 2002: 135(3):663-72. - Effects of intracoronary low-dose enalaprilat as an adjunct to primary percutaneous transluminal coronary angiography in acut myocardial infarction.
Kurz T, Schäfer U, Dendorfer A, Hartmann F, Raasch W, Tölg R, Remppis A, Giannitsis E, Dominiak P, Katus HA, Richardt G.
Am J Cardiol 2001: 88(12): 1351–1357. - Cardiac potentiation of bradykinin in patients with acute myocardial infarction.
Schäfer U, Kurz T, Richardt G.
Coronary Artery Disease 2001: BX21C0450: 479–483. - Neurohumoral activation in percutaneous coronary interventions: apropos of ten vasoactive substances during and immediately following coronary rotastenting.
Jain D, Schäfer U, Dendorfer A, Kurz T, Lindemann C, Tolg R, Hartmann F, Katus HA, Richardt G.
Indian Heart J 2001: 53(3): 301–307. - Presynaptic regulation of cardiac norepinephrine release in ischemia.
Grimm M, Kurz T, Schwarz M, Richardt D, Schäfer U, Katus HA, Richardt G.
J Cardiovasc Pharmacol 2001: 38: 58–68. - Potentiation of the vascular response to kinins by inhibition of myocardial kininases.
Dendorfer A, Wolfrum S, Schäfer U, Stewart JM, Inamura N, Dominiak P.
Hypertension 2000: 35(1): 32–37. - Effects of agmatine on the cardiovascular system of spontaneously hypertensive rats.
Schäfer U, Raasch W, Qadri F, Chun J, Dominiak P.
Ann NY Acad Sci 1999: 881: 97–101.